Sentence examples for cleavage affected from inspiring English sources

We investigated whether E-cadherin cleavage affected their integrity.

We therefore investigated how SpeB cleavage affected the antimicrobial activity of these three chemokines on S. pyogenes strain AP1 of the important M1 serotype.

To establish whether the reducing conditions used during MESNA cleavage affected the sdAb-aGST-MESNA produced in this manner, its interaction with GST was studied using Surface Plasmon Resonance SPRR).

As functional trimers are cleaved at this site, the question arises as to whether cleavage affects the antigenic structure of the Env complex in a way that is relevant to vaccine design.

To examine how the cleavage affects MsrB1 activity, we engineered a factor Xa cleavage site at the predicted cleavage site within MsrB1.

It is currently unknown how calpain cleavage affects SMN function, however, it is tempting to speculate that calpain cleavage could lead to altered protein interactions or might regulate an activity of the SMN complex through incorporation of the cleavage products.

However, several lines of evidence indicate that the PMA-induced ADAM17-mediated HB-EGF cleavage affects only HB-EGF molecules already present at the cell surface [7], and consistent with this, we here observed that mainly glycosylated forms of HB-EGF are shed upon PMA-treatment.

The structural studies clarify how S1 cleavage affects the conformation of the Notch1 NRR, and the studies of trafficking and signaling by Notch1 and Notch2 receptors engineered to be S1 resistant highlight the difficulties in generalizing conclusions based on studies of single Notch receptor family members.

Whether collagen that is resistant to cleavage affects SMC aging is not known.

To address whether cohesin cleavage affects recruitment of SAC components to kinetochores, we analyzed on chromosome spreads the distribution of Bub1.

On the contrary, neither of the glycosidase cleavages affected reactivity of IgM-type control serum antibodies (data not shown).