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In contrary to our expectations, cIAP-1 KO mice were clearly sensitized for pulmonary infection with C. pneumoniae, strongly supporting a role of cIAP-1 in the immune response against these obligate intracellular bacteria.
Knock-down of both surface-regulators clearly sensitized tumour cells to complement attack.
Unexpectedly, Slug overexpression did not mediate drug resistance but clearly sensitized lung cancer cells to TBAs in our investigation.
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The results clearly sensitize us to the need for institutions to demonstrate that they value mentoring.
Addition of FTC also clearly sensitizes the BCRP positive cell line OCI-AML6.2 to pHH3 down-regulation at barasertib-hQPA concentrations as low as 10 nM (p = 0.021) with complete down-regulation of pHH3 seen at 100 nM barasertib-hQPA with the addition of FTC).
Figure 3B clearly indicates that APE1 deficiency sensitized RPMI-8226 cells to melphalan; meanwhile, overexpression of APE1 rendered 8226 cells with enhanced resistance to melphalan.
It is important to note that our previous study clearly demonstrated that vessels are getting sensitized to noise-induced vascular damage rather than getting habituated since the blunting in FMD was in particular evident, when subjects were exposed first to 30 and then to 60 night noise events [ 6].
The data presented here clearly show that the hypogravity environment greatly sensitized the CD133 cells to various chemotherapeutic agents.
In our experiments, Nec-1s wableble to completely block TRAIL-induced necroptosis (but had no effect on apoptosis; P for Mz-ChA-1 cells was 0.045 and thus only marginally below the significance threshold of 0.05) either sensitized by HHT or CHX, clearly confirming the relevance of RIPK1 in HHT- or CHX-enhanced TRAIL-induced necroptosis.
This study clearly demonstrates that spinal cord neurons are sensitized in chronic pain after whiplash and in patients with FM; because the stimuli were delivered at random time intervals and the latency of EMG response was measured, voluntary symptom amplification could be ruled out.
Additionally, the data presented in this study clearly show that the hypogravity environment, by stimulating CD133 to proliferate, sensitized the CD133 to the various chemotherapeutic agents tested.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com