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This ability is clearly not essential for abstract, analytical observations of the heavens and construction of new technologies, such as telescopes.
It is clearly not essential in S. cerevisiae, as it is absent in Malaysian isolates.
QSOX is clearly not essential for eukaryotes, however, as yeast appear to lack the enzyme entirely.
Genes from the male-specific part of chrY are clearly not essential for life, as demonstrated in female organisms.
Thus, while O-fucose is clearly not essential for all Notch signaling, it might still have a modulatory role in some contexts.
Nevertheless, since cells can efficiently internalize the same particles in the absence of CD13 engagement, CD13 is clearly not essential for phagocytosis.
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The specific RNA binding of Gadd45a is clearly not absolutely essential for its demethylating activity, as shown by the K45A mutant.
Thus, clearly Leishmania MCA is not essential for cell death processes even though cell death is exacerbated when MCA is overexpressed.
Nevertheless, the ability to generate live offspring utilizing gametes from both Sirt1−/− males and females (Table 1 and reference 20) clearly shows that Sirt1 is not essential for embryogenesis.
For that reason fluency in the original language may well be a huge bonus in theatrical transposition – in Michael Frayn's Chekhov or Michael Meyer's Ibsen, clearly it is – but it is not essential.
"I thought I was essential, but I'm clearly not," he said, adding, half joking, "I'm going back to Tasmania, to the farm".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com