Sentence examples for clearly downstream from inspiring English sources

As expected, dopaminergic systems are clearly downstream of Comt, including Maoa in the striatum, DRD1 and DRD2 binding density in multiple brain regions, and the response to the dopamine receptor antagonist haloperidol.

Importantly, while mTORC1 is clearly downstream of Akt, its activation can lead to feedback inhibition of insulin signaling to Akt through effects on the insulin-receptor substrate (IRS) proteins (reviewed in ref. [38]).

However, KNL-2 localization is not fully lost and CENP-C is clearly downstream of KNL-2 in other model systems (Maddox et al. 2007 ; Fujita et al. 2007 ).

Clearly, the downstream effects of EGFR signaling reveal the oncogenic potential of aberrant EGFR signaling.

Determining how diabetes changes protein distribution and amounts is paramount, as these changes clearly have downstream effects within the cells that may be linked to cell proliferation and migration.

Both responses to α-MSH appear to be linked to the cAMP signalling pathway, but clearly the downstream signalling from the MC-1R is complex and far from resolved.

Clearly, proteins downstream of K-Ras, including A-Raf and B-Raf (both serine threonine MAP kinases) showed greatly increased expression in CAsE-PE cells compared with control (2.6- and 3.1-fold, respectively).

This mutation has effects on COMT activity and is clearly linked to downstream variation in expression of many other genes, dopamine tone, and behavior.

Moreover, molecules produced by the testes clearly have important downstream effects on female reproductive biology in Teleogryllus.

This survey allowed us to identify SSRs located within Open Reading Frames (ORFs) or clearly upstream and downstream of 5' and 3' untranslated regions (UTRs), respectively.

Although the inhibitory activity of bortezomib is clearly defined, the downstream mechanisms of cytotoxity remain poorly understood and at times controversial.