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Through a clearly defined trial and error procedure, the water evaporation induced drop in the thermal conductivity, and the void size that gives the best agreement between numerical prediction and high temperature tests are obtained to quantify the gypsum thermal conductivity temperature relationship.
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This effect was clearly seen in animal models of atherosclerosis because they have extreme gene defects, with defined trial diets, special experimental environment and limited immunological challenges.
Outcome Measure sentences: The efficacy and safety of an intervention are measured with outcome measures that should be clearly defined in the trial protocol.
Inclusion and exclusion criteria were clearly defined in all trials.
The systematic reviews [ 2, 16] raised some methodological concerns: "Falling" was not always clearly defined and many trials were not powered adequately to detect clinically relevant effects.
While criteria for progression have been clearly defined in clinical trials, the identical criteria may not be applicable to clinical practice.
The other camp would counter that it is inappropriate to administer products if the risk/benefit ratio has not been clearly defined in clinical trials.
However, given the standardization required, such as the requirement for a robust trial design with clearly defined inclusion and exclusion criteria, such trials do not capture all information that is relevant for clinical practice.
Trials on psychological interventions typically use other control groups (usual care, waiting lists or not clearly defined pharmacological treatment) than trials on pharmacological interventions (which are usually placebo-controlled or compare two pharmacological treatments), tend to have longer duration and often use other measurement scales.
15 The authors emphasised that caution is needed in recommending aquatic exercise interventions because of the limited number of trials in the meta-analysis and suggested that trials with clearly defined patient groups with long term outcomes are needed to further test aquatic exercise.
On the basis of the work conducted by an Assistance publique-Hôpitaux de Paris Espace éthique group in collaboration with parents, healthcare personnels and a philosopher, phase I therapeutic trials can be considered to be an ethically acceptable proposal provided the criteria and risks of inclusion in such a trial are clearly defined.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com