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When equal quantities (500 pg) of XDsh-CΔ8 or wild-type XDsh mRNA were injected into the dorsal region of 4-cell Xenopus embryos and luciferase activity was assayed at the late gastrula stage, XDsh-CΔ8 cleactivatedvAP1-luciferaseeractivityvity more strongly, indicating that Dvl in the open conformation activates JNK more potently than Dvl in the closed conformation.
Furthermore, exposure to dairy PM clearly activated NF-κB binding activity in the U937 macrophages.
The invasiveness of the cells and the activity of MMP-2 and MMP-9 were clearly activated by HA treatment, and blocked by CD44 neutralizing antibody.
Although our data do not show a wide activation of senescence-related genes, several senescence transcription factors were clearly activated with an expression trend correlated to glyoxylate cycle and to many stress response genes, indicating the activation of early heat stress-induced senescence in Cappelli.
Further, it clearly activated Nrf2 nuclear translocation and upregulated GCLC mRNA transcription and protein expression in dose-dependent manner, and its cytoprotection was reversed by GCLC protein inhibitor.
However, in the slow non-words condition the dyslexics were characterized by activations in the Lt IFG (Broca's area) and operculum, while the control readers clearly activated visual processing areas (extra-striate cortex).
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Apoptotic staining, DNA fragmentation, and flow cytometry analysis further demonstrate that treatment of Cdte QDs together with DNR can clearly activate apoptosis in HepG2/ADM cells.
We observed that Cdte QDs treatment could reduce the effect of P-glycoprotein while the treatment of Cdte QDs together with DNR can clearly activate apoptosis-related caspases protein expression in HepG2/ADM cells.
Nevertheless, S. Typhimurium can clearly activate caspase-1 in the absence of flagellin, and SopE contributes significantly to this effect.
In our study, both SNC80 and ARM390 clearly activate a signaling cascade that leads to pain inhibition.
While Bcd clearly activates expression of several gap domains, it is possible that gap gene cross-regulation governs the exact boundary position and sharpness of gap domains.
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