However, the dynamic experimental results showed no clear accumulation, which is close to the recovered rotating band after firing.
Within the cellular proliferation inhibition assay and western blot analysis, compound 3e demonstrated excellent anti-proliferative activity against solid tumor cells and clear accumulation of ubiquitinated cellular proteins.
The lymph nodes had a clear accumulation of tracer, which facilitated the identification even in the absence of appropriate optical filters (Additional file 1).
As expected, a clear accumulation of IR fluorescence was found at the tumour site, for the HER2- and CAIX-specific probes.
In such patients, we see a relatively slow, but clear, accumulation of activity in the RBM, which is most visible on the later scans.
The imaging was performed up to 48 h postinjection (p.i .. Already 3 h p.i., a clear accumulation of the fluorescent probes was seen in the tumours for each of the three probe combinations (Fig. 1a, red arrows).
The potential value of I2-PARPi as a tracer for clinical imaging of glioblastoma was corroborated in an orthotopic U251 MG glioblastoma mouse model by both SPECT/CT and PET/CT imaging (Figs. 8 and 9), where a clear accumulation of the tracer in the tumor tissue could be observed.
Moreover, a clear accumulation of fluorescence of GFP-Sep1-3 fusions was observed at the distal pole of filament emergence (Fig. 9B).
Immunofluorescence analysis showed a clear accumulation of TP03_0882 SVSP in vesicular structures, supporting the notion that SVSPs are incorporated into the parasite secretory pathway.
No clear association was found between divergent genes and transposable element abundance as illustrated by the S1 locus, where a clear accumulation of TEs was observed in CG14 compared to Nipponbare [27], with no significant effect on gene divergence.
