Sentence examples for cleared brain from inspiring English sources

Building on our previous finding that the full IgG 22C4 directed against the C-terminus of Aβ cleared brain amyloid, we tested whether an antibody fragment derived from 22C4 IgG retained this activity [31], [32].

Briefly, 0.5 ml samples of 10% (wt/vol) cleared brain homogenates prepared for CDI analysis in 2% sarkosyl/PBS (see below) were diluted with a further 0.5 ml of 2% sarkosyl/PBS and incubated for 10 minutes at 37°C.

Briefly, cleared brain extracts prepared in lysis buffer (0.1% Triton X-100, 1× PBS, pH 7.4, 1× Complete Protease Inhibitor cocktail [Roche Applied Science]) derived from whole brains of adult WT and LRRK2 KO mice were injected for FPLC on a Superdex 200 10/300 GL column (Amersham Biosciences).

They developed a pipeline which included semiautomated acquisition and analysis of data from cleared brains acquired using light-sheet microscopy.

Because we wanted to characterize the distributions of all labeled neurons across brains, we decided to use light sheet microscopy on cleared brains.

In order to quantify the spread of rabies virus in each condition, we cleared brains using CLARITY to prepare them for light sheet microscopy.

In the case of AD however, these cells may be therapeutic in clearing brain deposits of aggregated Aβ peptide if induction of a phagocytic state can be achieved [5].

Our study revealed that the peripheral system is potent in clearing brain Aβ and preventing AD pathogenesis.

2CA rapidly suppressed T cell autoreactivity, clearing brain and spinal cord infiltrates, through selective removal of newly activated T cells.

The present study reveals the importance of natural Aβ catabolic capacity of the peripheral system in clearing brain Aβ.

The physiological capacity of peripheral tissues and organs in clearing brain-derived Aβ and its therapeutic potential for AD remains largely unknown.