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Therefore, regular airway clearance therapy was essential [23, 24, 26].
Treatment of lung disease is based upon airway clearance therapy and aggressive antibiotic.
13, 14 In one study, adherence to airway clearance therapy in patients with cystic fibrosis was analyzed by GBTM.
Nevertheless, in COPD patients, there is a pathophysiological rationale for the use of a mucus clearance therapy.
Although inspiratory muscle training was applied as a form of airway clearance therapy (ACT) in this study [ 18], no beneficial effects on ease of sputum expectoration were demonstrated.
Children were asked to stop bronchodilators, rhDNase (dornase-alpha), and airway clearance therapy for 12 hours before and during each study visit.
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The next generation of amyloid clearance therapies are currently under development.
Airway clearance therapies are likely to function in synergy with antimicrobial therapy to accelerate resolution of airway infections.
Our study group had a significantly higher usage of nebulised rhDNase (100%) and other mechanical airway clearance therapies (97%) compared with previous studies.
Methods of treatment directed against the onset of decompensation are attractive in theory, although the benefits of mucus clearance therapies have been regularly challenged [ 6- 10].
5 8 During acute CF lung disease exacerbation, usual treatment involves intravenous antibiotics, enhanced nutritional supplementation and airway clearance therapies (eg, frequent chest physiotherapy, inhaled albuterol, aerobic exercise).
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