Sentence examples for clearance characteristics from inspiring English sources
Surprisingly, despite improving CXCR4 affinity of the ligand, the exchange of DOTA by NOTA had deleterious effects on overall pharmacokinetics, both with respect to CXCR4 targeting efficiency and clearance characteristics.
Its clinical efficacy may result from its unique binding and clearance characteristics and receptor down-regulation mechanisms.
Functional asplenia results in very slow parasite clearance after artesunate treatment, resembling the clearance characteristics in the described case (5 ).
This indicates that the increase in depolarization-induced glutamate release was not the result of altered clearance characteristics in the Tg mice.
Similar to the vascular clearance characteristics, the amount of Dex40 retrieved in urine was higher than that of Dex70, i.e., about 35-40% of the injected amount, and comparable for all three animal groups.
The βENaC-Tg mouse features airway surface dehydration and reduced mucus clearance characteristic of CF and phenocopies key features of CF lung disease including early-onset airway mucus plugging, spontaneous bacterial infection, chronic inflammation, and structural lung damage [29, 30, 34, 35, 57, 61].
Defects in mucus clearance are characteristic of muco-obstructive pulmonary diseases of genetic or environmental origins, e.g., cystic fibrosis (CF), primary ciliary dyskinesia (PCD), and the chronic bronchitic (CB) form of chronic obstructive pulmonary disease (COPD) [ 1].
The influence of tip clearance on the characteristics of the basal meter is studied.
In total, matuzumab showed similar PK characteristics (clearance and volumes of distribution) to other therapeutic mAbs following intravenous administration (Mould et al, 1999; Kovarik et al, 2001; Bruno et al, 2005).
The other two studies included the most of patients with favorable characteristics (creatinine clearance more than 60 ml/min and good performance status) [ 21, 22].
