Lactate clearance capacity and the maximal lactate steady state.
Convection has an advantage over diffusion in the clearance capacity of IL-1ra, but is associated with greater plasma protein losses.
It is also well documented that the frequency of sliding hiatal hernias, which affect the clearance of reflux material from the distal esophagus, increase with age.24 Furthermore, the clearance capacity may be impaired in the elderly as a consequence of disturbances in esophageal motility and saliva production.
We suggest that such technetium-99m-labelled engineered vesicles may be of aid for detection of the liver and spleen macrophages with enhanced phagocytic clearance capacity by gamma scintigraphy.
Intravenous injection of an endotoxin-free solution of poloxamine-908 to rats can enhance the phagocytic clearance capacity of tissue macrophages, particularly those of the liver and the spleen.
We used Pseudomonas aeruginosa strain UI-18 (PA-7) (ATCC, Manassas VA, USA) to examine the phagocytic and bacterial clearance capacity of NB4PMN cells according to previously described methods [27].
In theory, overwhelming NETosis or a reduced clearance capacity of NETs could be detrimental to the host during sepsis and contribute to ongoing inflammation, organ damage, and/or exhaustion of the immune system [21].
However, we found no correlation between the clearance capacity and TNF-α secretion by lupus monocytes (p = 0.267, R = 0.26) (Figure 3).
If the amount of immune complexes exceeds the clearance capacity of mesangial cells, this could result in release of immune complexes into the mesangial matrix surrounding these cells.
However, independently of the clearance capacity of lupus phagocytes, the direct effect that apoptotic cells might have on the function of lupus phagocytes has not been explored.
