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The cellular immune response is thought to play a major role in the clearance and control of the virus and failure of cellular responses to HCV is a major factor for chronic viral persistence [2] [4].
There is mounting evidence that NK cells are involved in the clearance and control of HCV infection, including associations between NK cell dysfunction, chronic HCV infection, and the pathogenesis of liver disease [ 14, 35, 36].
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Raw biodistribution data for blood clearance and controls are available in supplemental data (Additional files 3 and 4).
By suppressing AM cytokine gene expression PT may be modulating the number and function of other effector immune cells required for viral clearance and controlling lung inflammation.
Cystic fibrosis (CF) lungs are usually susceptible to Pseudomonas aeruginosa colonization and this bacterium is resistant to immune system clearance and drug control.
These include costs for documents, administrative fees for customs clearance and technical control, customs broker fees, terminal handling charges and inland transport.
The mechanisms of senescent cell clearance and SASP control are not yet known.
Despite the benefits of high-intensity renal replacement therapy, including superior hemodynamic stability, metabolic clearance and volume control, no survival advantage can be demonstrated with its use [ 25].
Genetically engineered mouse models have provided abundant evidence for the important role of autophagy in mitochondrial integrity, intracellular protein clearance and ROS control.
Glial structural changes are not only involved in modifications of the number of synaptic inputs but can also affect synaptic efficacy due to their participation in glutamate clearance and by controlling extracellular ionic concentrations thus changing neuronal excitability (39).
Failure of FcγR-mediated clearance of ICs and control of inflammatory responses are thought to be a predisposing factor to SLE.
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