Based on the above findings showing a clear-cut activity of MT2 in several in vitro systems, we wanted to assess its ability to rescue NGF deficit in a recently characterized rat hippocampal neuronal model, in which NGF deficit is strictly connected to the activation of the amyloidogenic pathway.
This lack of clarity is partly because knowledge work involves more diverse and amorphous tasks than do production or clerical positions, where the relatively clear-cut, predictable activities make jobs easier to automate or streamline.
Uncovering the role of 5-HT4 receptors in the gastrointestinal tract and the development of selective 5-HT4 receptor agonists that have clear-cut prokinetic activities offered great opportunities for the treatment of patients with different types of chronic constipation.
Previously, the immigration service could set aside judges' rulings only in cases of clear-cut criminal activity, situations that are unusual because judges generally impose high or no bail in such cases.
As observed by Stair-Nawy and colleagues [ 28], the fibroblast preparation (lanes 1) exhibited a clear-cut band of activity with an apparent molecular weight of approximately 55 kDa at pH 4, but no activity was detected at pH 6.5.
Per cent distributions evidenced a clear-cut difference in walking activities (46.25% in Wistar, 28.4% in DA/Han rats) and in the sniffing activities (45.82% in Wistar, 62.54% in DA/Han).
By simplifying my life I'm referring to discipline, effectiveness in juggling my multiple activities, clear-cut choices and decisions.
Prices of Treasury notes and bonds declined modestly yesterday, as dealers said there was no clear-cut trend in investor activity to provide direction to the credit markets.
"This proposed guidance is a first critical step toward creating clear-cut definitions of political activity by tax-exempt social welfare organizations," said Mark J. Mazur, the assistant Treasury secretary for tax policy.
In a press release Tuesday, Treasury Assistant Secretary for Tax Policy Mark J. Mazur called the proposal "a critical step toward creating clear-cut definitions of political activity by tax-exempt social welfare organizations".
