Exact(19)
We interpret these data to indicate that, although the Ubx profile closely mirrors chromatin accessibility, Ubx does not bind non-specifically but rather shows clear specificity for Hox PWM motifs within accessible chromatin.
Structural studies on Ogt provided insight into how this enzyme modifies this baffling diversity of substrates: Ogt primarily binds to the peptide backbone of substrates and shows no clear specificity for the modification of specific serines or threonines (Janetzko and Walker 2014).
The physicality of it, and the clear specificity of what the project required of me, was a balm.
These variants are large and affect many genes but lack clear specificity toward autism as opposed to developmental-delay phenotypes.
Neither of the tested Err1 proteins from the three fungi has a clear specificity for D-erythrose over D-threose or vice versa.
In Experiment 2, this time range did not even show clear specificity to stimulus type.
Similar(41)
Studies in yeast [5], [6] have shown that kinases can be promiscuous, phosphorylating hundreds of proteins, but they also have clear specificities.
We also found that there were several Papilio-specific genes with clear marking specificity, suggesting that species-specific genes contribute to marking formation.
Even among the yeasts, modes of centromere inheritance vary, from complete genetic specification, as in Saccharomyces cerevisiae, to genetic specification without clear sequence specificity, as in Schizosaccharomyces pombe (Polizzi and Clarke 1991), to complete epigenetic inheritance, as in Candida albicans (Ketel et al. 2009).
Interestingly, as reported in humans [ 14], the majority of alternative splicing events showed clear tissue specificity, demonstrating the importance of alternative splicing in tissue specific programs of gene expression and its major roles in functional complexity.
The most striking aspect of the identified association of the rs729749 SNP is the clear sex specificity, indicating that the disease pathway affected by the rs729749 SNP is specific to men.
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