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Although no clear replication pattern was observed in actively bloodfeeding and ovipositing fleas, there was an inverse correlation between colony R. felis-infection prevalence and R. felis-infection load in individual fleas.
We did not observe clear replication of our two top loci that were genome-wide significant in our CARe GWAS.
Expression of the Twinkle S369P and A359T mutations had the mildest effect, although also they resulted in clear replication stalling and a shift to less RNA-containing intermediates.
This life cycle calls for a clear replication and regulation of genome content and the capacity to mark and separate the genome to be inherited by the offspring.
The first GWA scan for type 2 diabetes (and all others that followed) was validated by the clear replication of the TCF7L2 association (21).
While there was no clear replication of this BMI-AA association in an independent cohort (the KORA cohort), the modelling of AA is in its infancy, and studies have found this BMI-AA association in liver tissue (7).
Similar(52)
As a consequence of the inability of ATMIN-deficient cells to clear replication-induced stress, these cells displayed an increase in lagging chromatin and anaphase bridges after aphidicolin treatment (Fig. 5C).
These data indicate that ATMIN has functions independent of ATM in clearing replication stress.
In these models, there is a clear viral replication rate threshold beyond which the number of cancer cells drops to levels of the order of one or less, corresponding to extinction in practical terms.
As should be clear, individual replications entail a trade-off between levels of generality and tests for validity (Table 1).
This is enigmatic since it is not clear how HCV replication start without CAHL, which positively plays HCV replication, at very beginning of HCV infection in normal liver cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com