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There was a clear predisposition to hand trauma for males, manual workers, combat soldiers and engineers/mechanics.
There is a clear predisposition towards initial and recurring bouts of toxic shock syndrome among menstruating women lacking pre-existing antibodies against TSST-1 [16], [16].
These patients also had clear predisposition to other severe infections with intracellular microorganisms such as atypical mycobacteria, Salmonella spp., Listeria monocytogenes, and Leishmania spp (1 – 5 ).
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Nevertheless, I believe that we should view preventive mastectomy -- at least for women without a clear genetic predisposition to breast cancer -- as a last-ditch measure.
Approximately 10% of cases of epithelial ovarian cancer (EOC) are associated with a clear hereditary predisposition to disease; the vast majority of cases resulting from inherited alterations in the breast cancer-associated tumor suppressor genes 1 or 2 (BRCA1 or BRCA2) (reviewed in: [1], [2], [3]).
The most clear hereditary predisposition syndrome associated with ESCC is tylosis.
While in some individuals there is a clear genetic predisposition, other cases of AAA seem to arise spontaneously [ 121].
At this time there appears to be no consensus as to whether there is a clear genetic predisposition to developing sporadic post-traumatic NHO.
Few causative factors have been identified: familiar forms are rare (about 1%); there is no clear genetic predisposition, and presumably tumorigenesis may require alterations in more than one gene.
The most clear defined hereditary predisposition associated with ESCC is palmoplantar keratoderma (PPK).
In this way, we sought to get a clear picture of the predisposition to organ metastases for Chinese triple negative breast cancer patients, thereby, shedding more light on the underlying distinction in biological behavior between different subgroups.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com