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A therapy that apparently seems to work in some indication (or in some subpopulation) where it was previously either believed not to work, or had never been looked at, may simply be the result of a Type I error: a clear multiplicity issue.
Finally, when the Pol δ mutator allele pol3-Y708A was combined with the pol2-4, the double pol3-Y708A pol3-Y708A pol2-4 pol2-4ar mutantlicity for forward mutationshowedhe clearlocus – a 21-fold increase for the pol2-4 pol3-Y708A double multiplicityred to a 3.8-ford increase forward2-4 and a 6.3-fold increase for pol3-Y708A (Table 5).
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A membrane reactor with separate reactants feed for the catalytic combustion of propane was studied in the transition from the kinetics- to the transport-controlled regime, where a clear steady-state multiplicity phenomenon takes place.
Although most of the changes in individual metabolites were not statistically significant after correction for multiplicity, clear trends were observed.
It is clear enough that the multiplicity of overlapping digital networks brings students and teachers new ways to conduct research, to establish communities of interest, and to facilitate learning.
Cells were transduced with cleared supernatants at a multiplicity of infection of 10, in 3 ml of culture medium and polybrene (Sigma) at 8 μg/ml, for 8 h.
Inspired by early Renaissance art and the works of Albrecht Dürer, Schnorr's oil paintings were characterized by a precise linearity, clear bright colours, and a multiplicity of symbolic detail.
The resulting multiplicity is a clear signature of the particle type.
For, as the tendency and the multiplicity theories made clear, instinct and intelligence are not simply self-contained and mutually exclusive states.
Improvement in the imaging capabilities of CTP does allow for a non-invasive assessment of the cerebral circulation dynamics, but it is liable to the inter-evaluator variability and lack of clear interpretation paradigms given the multiplicity of variables involved in generating and influencing these images [9, 10].
While the latter result did not reach statistical significance, there was a clear trend toward decreased tumor multiplicity throughout the course of the prevention experiment.
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