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The outcome indicated that both acetoin and 2,3-butanediol showed clear impairment on γ-PGA production of B. subtilis ZJU-7.
A potential third group, i.e., SKOV3 and UPN251, appeared to behave in a single cell manner with less clear impairment or remodeling upon ECMs (Figure 1D).
In our experiments Dyrk1a+/− mice showed a clear impairment of novel object recognition performance in the simple task relative to wild type mice.
Inhibition of Src kinases indeed resulted in a block of inflammatory cytokine release resulting in a clear impairment of Th1 differentiation [25].
We observed that under stressful conditions the hybrid strain showed a clear impairment in resistance to hydrogen peroxide and decreased survival within U937 culture monocytes.
By contrast, a recent study concluded that shifting a subjects' viewpoint during the memory delay of an object-location task decreased performance regardless of hippocampal integrity, whereas increasing memory load led to a clear impairment in adult patients with acquired hippocampal damage [21].
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A cognitive test of object placement recognition showed clear impairments of hippocampal spatial learning and memory in SPLfl/fl/Nes mice (Fig. 1e).
Despite clear impairments in reading non-words, good performance on a variety of phonological tasks makes the possibility of generalised phonologically based disruption unlikely.
A detailed reading of the literature reveals that rodents treated with LPS or IL-1β, whether systemically or centrally, do not reproducibly show clear impairments in spatial reference memory in the Morris Water Maze.
In its order, the S.E.C. said that "we consider independence to be a keystone of our disclosure system" and that senior officials of KPMG "failed to undertake any reasonable inquiry that necessarily would have led them to discover clear impairments of independence".
Consistent with results from the db/db mice, wound macrophages derived from NOD as well as from Akita mice showed increased number of apoptotic cells in wound tissue (data not shown) as well as clear impairments in dead cell clearance activity (Figs. 4C&D).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com