Exact(6)
To comparatively evaluate the clinical and microbiological profiles and treatment outcome of cases with post-penetrating keratoplasty (PK) infectious keratitis in failed and clear grafts.
Several factors have been considered to affect post-DSAEK visual outcome in clear grafts and in absence of ocular comorbidities.
The best corrected visual acuity of the 28 clear grafts ranged from 4/60 to 6/9.
Of the 53 eyes with regrafts, 28 eyes (52.8%) had clear grafts at the end of follow up of which, 25 eyes (89.3%) had undergone single regraft and 3 eyes had multiple regrafts (Table 2).
Nevertheless, even in presence of clear grafts, the percentage of patient achieving a BCVA of 20/20 is relatively small, and it is also well-known that DSAEK leads to a small hyperopic shift [ 9– 11], residual corneal aberrations, glare and reduced contrast sensitivity compared to normal [ 4, 5, 12– 17].
In order to determine whether prolonged corneal survival of allografts after LN removal was due to "ignorance" of priming via draining LN cells or suppression by spleen derived T regulatory cells, we have adoptively transferred splenocytes from post-LN removal tolerant mice with clear grafts to naive mice prior to corneal grafting.
Similar(54)
Fig. 1 Clear graft following TPK Fig. 2 Pinpoint leakage on FFA in RE.
The patient who underwent DSAEK with this technique had improved visual acuity and a clear graft at five months.
Postoperative follow up for 16 weeks showed a clear graft with 0.3 visual acuity.
All patients had a clear graft at the latest follow-up visit.
In the early postoperative period, the result indicated a clear graft.
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