We have a clear-cut challenge here, and it must be met with an equally clear-cut response.
(She was asked directly how she intended to prevent the investigation dragging on "for year after year after year" — but had no clear-cut response to that).
Ten percent of cells displayed a less clear-cut response with delayed (Fig. 2C ) or no definitive spreading (Fig. 2D ).
The only patient who showed a less clear-cut response either in terms of severity and activity indexes was the one with a long-standing disease.
Though results on urinary L/R ratio were disappointing, results on symptoms reported by patients during the challenge provided a clear-cut response, indicating that a single low dose of Tm is well tolerated by CD patients.
The lack of clear-cut responses by the studied biomarkers, even when only in presence of Cd, do not allow insights into the effect of the presence of nTiO2 on the Cd toxicity to the bivalves.
First, the response of depressed subjects to medication varies widely: both fast and clear-cut responses and no response at all have been reported and second, the placebo response is relatively high and variable.
The response seemed clear cut – remove al-Qaida from Afghanistan, capture Bin Laden and topple his Taliban facilitators so that al-Qaida can't take root there again.
"Generally speaking how would you rate the condition of Delaware's economy... excellent, good, not so good, or poor?" This seems like a clear cut question, but the topline response categories presented by Pulse raise some addition concerns.
While for normal cells there was a subdued response with no clear cut dose dependence, a gradual loss of viability was observed for cancer cells as the IONP concentration was increased gradually from 1 μg/ml to 100 μg/ml.
Her response is not clear cut, but recalls how murder left an impact on her that could not be fixed.
