Despite the significant decrease of transmitted NRTI resistance there is no clear cut decrease of either the prevalence of TAMs or the T215 revertant substitions (figure S1).
In line, we found no clear cut decrease in the local expression of IL-1β and IL-6, even though these are produced by B cells, T cells and macrophages.
Next, we decreased anti-CD3 surface density, inducing clear-cut decreasing T-cell/particle interactions.
No clear-cut decrease in telomere length was observed, suggesting a better repair of telomeric ends in natural background area.
Second, studies with a monitoring period of at least 6 months demonstrate a clear-cut decrease in compliance over time suggesting that the effect of awareness of being monitored wanes over time [ 20- 22].
No plasmid DNA was found in the organs distant from the injected muscle (liver, spleen, kidney, gonads, heart, lung brain and distant muscle). ET of 50 μg pCOR/sTNFRI/IgG1 plasmid at the onset of clinical disease induced a clear-cut decrease in clinical signs of arthritis.
No plasmid DNA was found in the organs distant from the injected muscle (liver, spleen, kidney, gonads, heart, lung, brain and distant muscle). ET of 50 μg pCOR/sTNFRI/IgG1plasmid at the onset of clinical disease induced a clear-cut decrease of clinical and histological signs of arthritis.
Our data suggest that i) expression of TNFR1 IgG does not impair the ability of lymphocytes to migrate to areas of inflammation and ii) there is no clear cut correlation between decreased saliva flow and the severity of inflammation within the glands.
Sometimes it's less clear cut.
Arkansas: This one looks pretty clear cut.
Legally it's not very clear cut".
