The public health benefit of TasP is not so clear and is being specifically addressed in 4 randomized trials being conducted in heterosexual populations in countries in sub-Saharan Africa with generalized epidemics [ 34, 35].
While the aetiology of Hodgkin's lymphoma is not totally clear, altered immune function and specifically late exposure to common viruses and Epstein Barr virus (EBV) are thought to play a role, and may also be involved in NHL.
The business case is arguably clearer: Major sporting events — and, specifically, major football clubs — have long seen their future growth in expanding and nurturing a global fan base.
This may imply that by rapidly and specifically clearing prothombotic PS-expressing microparticles, bavituximab may actually decrease the risk of thrombosis in cancer patients.
"When you're clear and you define what specifically we are looking at, then staff can go in and analyze that and look for the fiscal concerns, the enrollment impact and all the other impacts around this specific plan," she said.
She was an environmentalist ahead of her time and created several paintings that deal with her concern for the environment, and specifically the clear-cutting of forests (Odds and Ends, Above the Gravel Pit, Loggers Culls, Stumps and Sky, A Forest Clearing).
Interestingly the division between "accepted programs" and "questionable programs" is less clear, and Differentiators tend to address specifically each vaccination program.
The trial's aims will be described in a general way, as 'a study to make sure that written information about breast cancer screening is clear and helpful to women', without specifically referring to overdetection.
I could be wrong, but that's the whole point of simple models: to lay bare what you're assuming, and make it clear what, specifically, is driving your conclusions.
