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However, the dynamic experimental results showed no clear accumulation, which is close to the recovered rotating band after firing.
Within the cellular proliferation inhibition assay and western blot analysis, compound 3e demonstrated excellent anti-proliferative activity against solid tumor cells and clear accumulation of ubiquitinated cellular proteins.
The lymph nodes had a clear accumulation of tracer, which facilitated the identification even in the absence of appropriate optical filters (Additional file 1).
As expected, a clear accumulation of IR fluorescence was found at the tumour site, for the HER2- and CAIX-specific probes.
In such patients, we see a relatively slow, but clear, accumulation of activity in the RBM, which is most visible on the later scans.
The imaging was performed up to 48 h postinjection (p.i .. Already 3 h p.i., a clear accumulation of the fluorescent probes was seen in the tumours for each of the three probe combinations (Fig. 1a, red arrows).
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Galectin 3 was widely distributed in the synovium, with clear accumulations at sites of cartilage invasion [ 33].
Co-treatment with PS2 resulted in a much clearer accumulation of fluorescent protein in the cytosol, suggesting that ppl mCherry which failed to enter the ER in the presence of ESI was degraded via the proteasome.
Herein, we will review recent advances and also potential setbacks with respect to the myriad of therapeutic strategies that are designed to slow down, prevent, or clear the accumulation of either "pathological" Aβ or tau.
It is worth mentioning that in this case, a clear nuclear accumulation of GFP signal was observed.
As seen in figure 4B, in AngII-infused rats the MMP-9/TIMP-1 ratin in aorta was around 0,4-fold showing a clear matrix accumulation environment.
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