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Edd Weninger Overgaard, Ariz., May 12, 2010 To the Editor: Re "Cleanup Tools Remain 1990s Technologies" (news article, May 11): I was completely astonished by one line in your article.
In order to compare AFST with other EST cleanup tools or pipelines, we compared Genbank ESTs for two species with our processing results because these Genbank ESTs have been trimmed by other tools or pipelines.
Also due to the availability of the complete cDNA library construction information, we were able to use two other popular Sanger EST cleanup tools – Lucy [ 13, 14] and SeqClean [ 15] to process 309,976 raw ESTs for performance comparison with AFST.
Select "Cleanup Tools" from the options.
Click the "Cleanup Tools" button and select "Mailbox Cleanup".
CCleaner is much more comprehensive than using the built-in deletion (Disk Cleanup) tools that Windows provides.
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Windows' built-in Disk Cleanup tool will do the job, but Piriform's free CCleaner is a popular alternative.
Check the box next to "Delete all offline content" and click O.K. Now run the Disk Cleanup tool again.
To reclaim space, run the Disk Cleanup tool (Bring up the Start menu and type "disk cleanup tool" into the search box) to remove Internet cache files, clear the Recycling Bin and delete installed programs that you never use.
Reza Masoudi Compress Old Files is a feature of the Disk Cleanup tool (cleanmgr.exe) in Windows XP, but it does not delete files.
What might be causing this? A. The Disk Cleanup tool is intended to free up hard drive space by searching out and deleting old or unnecessary files, like downloaded files, programs you no longer use, superfluous Windows components and temporary files and Internet files.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com