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LOE was traditionally defined as "hierarchical grading systems for classifying study strength/quality" (Burns et al. 2011; Wright et al. 2003; Sutherland 2001; Oxford Centre for Evidence-based Medicine – The Oxford 2011; Petrisor et al. 2006).
These criteria did not mitigate difficulties classifying study patients, and there fore research remained limited.
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Classifying studies in TvN or Meta would be considered reasonable if the ratios of consistency were higher than those within the subgroups of interest.
Stratified analyses were performed by classifying studies into subgroups of sample source, dominant ethnicity, and malignant diseases.
Considering the large proportion of Chinese patients in the studies, we performed a stratified analysis by classifying studies into subgroups of ethnicity.
In order to seek possible explanations for heterogeneity, stratified analyses were performed by classifying studies into subgroups of sample source, ethnicity, and main cancer type.
This framework extends descriptive terms previously suggested by McGinn et al (2000) [ 17] as suitable for classifying studies of clinical prediction rules.
The heterogeneity was partly decreased in some subgroups when we conducted stratified analyses by classifying studies into subgroups of sample source, dominant ethnicity, and malignant diseases.
One problem lay in how we actually classified study design.
We classified study subjects according to tertiles of ΔGA/HbA1c.
The International Diabetes Federation criteria were used to classify study participants with the metabolic syndrome.
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