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In pathway level, according to the regulation of TFs on target genes, we classified regulations into three types: positive, negative or both positive and negative.
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Trying to create "buckets" to classify regulations broadly among the states is a challenge because most states have not enacted comprehensive legislation.
It is unclear, therefore, how these egg/mitochondrial donors will be classified when Regulations are (as we assume they will be) eventually placed before Parliament for approval.
These regulations are classified as certain regulations in our study.
Second, there is a small group of genes classified as "regulation of synaptic transmission" and similar categories.
The list also involves elongation factor 1 alpha (EF1alpha) and TFCP2 genes, which are classified as regulation-related genes, as well as glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene, which is categolized as energy metabolism-related gene (Table 4).
Each protected area was classified by its regulations on extraction (no-take, take, or multi-purpose) and risk of poaching (low, medium, high).
Finally, we look at whether the type of zoning regulations (classified as either "Traditional", "Exclusion", "Reform", or "Wild Wild Texas" zoning following [23]) or the level of conservation funding affects open space loss or land inequality.
It consisted of 3250 TF-gene regulations classified according to three types: activation, repression, and context-dependent effect; we assigned ' +', ' -', and ' ?' signs respectively to these three types of regulation.
Many authors classify microRNA regulation as a third epigenetic phenomenon.
For example, an analysis of yeast strains grown in different nutritional conditions combined Z-scores of metabolic fluxes obtained by either metabolic or gene expression measurements to classify the regulation level of metabolic circuits as transcriptionally, post-transcriptionally, or metabolically controlled [ 46].
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