Further, the addition of CAC to traditional risk factors resulted in a significant improvement in the classification of risk for the prediction of CVD mortality.
The findings indicate that a reliance upon dysglycemia as a demarcation of risk in autoantibody-positive populations could result in a less-than-optimal classification of risk for prevention trials.
Several clinicopathological parameters are currently used for the classification of risks for relapse and death, such as surgical stage, histological type, grade, depth of myometrial invasion, cervical stromal invasion, lymph node metastasis, lymph-vascular involvement, and peritoneal cytology (Morrow et al, 1991; Grigsby et al, 1992).
This finding suggests that determining the risk group using the NCI criteria may be imprecise and that the correct classification of risk is needed for the proper application of therapy to increase the chance that the patient can remain free of events.
Therefore, it is possible that the classification of risk may be inaccurate for a small proportion of study respondents given the limitation of no objective verification of self reported family history.
Clinical guidelines for classification of risk status were developed within each South Australian Dental Services health region.
"It is just a tool that will hopefully allow for the better classification of risk, but we need to think carefully about the downside if we misclassify an individual," she said.
In a recent article in BMC Cancer, Garrido-Estepa et.al. [ 8] compared four classification scales of risk categorizations for breast cancer based on mammographic density patterns from women included in the DDM-Spain study.
Classification of risk groups.
