Considerable variability occurs among experts [20, 21] and hospitals [18] in the classification of infections as CLABSI or secondary bacteremia.
Over recent years, a new, comprehensive recommendation on classification of infections caused by Gram-positive and emerging Gram-negative multidrug-resistant pathogens has been launched.
Considerable variability occurs among experts [ 20, 21] and hospitals [ 18] in the classification of infections as CLABSI or secondary bacteremia.
This has led to the creation of a new group among the traditional classification of infections, termed "healthcare-associated infections" (HCAI).
The classification of infections into late and early, periprosthetic/deep surgical site infection (SSI), and superficial SSI complicates comparisons between studies.
IFD were included in the classification of infection as MDIB (fungemia), MDINB (tissue invasion documented by culture) or CDI (probable or possible IFD without microbiological evidence).
It potentially could affect the classification of infection.
The possibility of a delayed rising of antibody titer post-infection, resulting in mis-classification of infection status among different groups, was also considered.
Difficulties in the classification of infection severity and the identification of organ dysfunctions could explain the differences between studies (30, 31).
The following classification of infection according to place of acquisition was used: CAI - infection detected within 48 h of hospital admission in patients without previous contact with healthcare services.
We applied the CDC definition of SSI using data from the medical record, but ultimately did not use the classification of infection types, because we are not convinced that it is reliable in the arm and leg.
