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For example, until very recently, most studies have included only binary classifications of exposure.
We had access to valid classifications of exposure, and complete follow-up (Danish National Board of Health, 2000; Knudsen, 1998; Roed et al, 1999).
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14 We decided on the classifications of exposures and causes of death before we linked the exposure and outcome databases.
For example, registries might have their own classifications of exposures or diseases, which might be more user friendly than the EU- shortlist of exposures [ 43] or the ICD-classification of diseases.
The significance of these epidemiological studies is, however, limited because of the small number of participants, mostly males due to the working structure in the companies, and the problematic classification of exposure [17, 115].
Nor is the classification of exposure exact enough to detect even very large effects of DDE.
As with many studies of air pollution, classification of exposure is imperfect.
Classification of exposure is another area where bias can be introduced.
There was a wide variation in classification of exposure across studies.
However, meconium tobacco smoke metabolite concentrations do not allow classification of exposure during specific time periods of development.
Newer data, however, suggest a single sample may allow a broad classification of exposure (Meeker et al. 2005).
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