Sentence examples for classification of variation from inspiring English sources

Classification of variation is therefore done as haplogroups that fit into a mitochondrial tree with a root estimated around 200 000 years back.

This approach eliminates the problems of alignment due to extensive divergence within the HVRs, and allows identification of closely related HVRs (in different protein variants), thus providing a ready classification of variation generated via point mutation versus recombination in recently divergent proteins.

Goodness of classification was determined using the area under the receiver operating characteristic curve, with 1 indicating perfect recognition of all alterations and 0.5 indicating random classification of the variation.

However, false positive and false negative detections often result from lack of sufficient variant evidence, contamination of the biopsy by stromal tissue, sequencing errors, and the erroneous classification of germline variation as tumor-specific.

The Ministry of Health may request the CMDh (Co-ordination Group for Mutual Recognition and Decentralised Procedures—Human) to provide a recommendation on the classification of the variation according to Article 5 of the regulation.

automated identification and classification of splicing variations found between clustered PASA alignment assemblies.

Annotation and classification of the variations into the different categories presented in Figure 1 was done by a custom Perl script.

MGBR2_ex19 27 is the largest reported BRCA2 minigene and constitutes a valuable tool for the functional and clinical classification of sequence variations.

In addition to the exhaustive registration of mutations found in the French population, the database presently contains the relevant data, allowing the classification of 370 variations either in (likely) neutral or causal.

The first 4 principal components (PC) account for 99.9% of the variation, and classification of the variance structure reveals distinct multi-scale topographic variation associated with different process-form regimes and evolutionary stages.

The long-term combination of (1) improved classification and annotation of variation data and (2) simple increase in available studies should allow us to find these cases and truly study the quantitative differences of heterozygous and homozygous states, ultimately helping to develop and refine possible detection assays.