Only molecular data were used for classification of specimens.
Classification of specimens into one of two predetermined classes based on gene expression data was performed with a compound covariate predictor.
Following discordant analysis by the PneumoBacter-1 multiplex assay and classification of specimens as per the definitions described above, the sensitivity and specificity of the ProPneumo-1 assay for C. pneumoniae was 100%and100%0%, respectively (Table 4).
A final subtype (bp-FISH) was then assigned to each specimen according to this tree, including classification of specimens as 'abnormal' if aberrations were present but did not result in an RCC subtype classification according to the tree and as 'normal' if no aberrations were detected.
The classification of specimens from south of the Betsiboka as L. edwardsi was, however, based on erroneous information on the extension of the species' range as far south as the Tsiribihina [ 3, 5], despite the report of the existence of L. ruficaudatus north of the Tsiribihina in the Antsalova region [ 4].
Data was analyzed by country income World Bank classification, type of specimen collection, level of support offered and other qualitative aspects.
Six parameters were recorded for all of the lesions: size (calculated longest diameter), palpability, sonographic classification, number of specimen per lesion, histological findings at LCNB, and excision biopsy.
The diagnosis and classification of each specimen was made or reviewed by an expert haematopathologist (JT) practising at our centre [ 10], according to the WHO Classification of Tumours of Haematopoietic and Lymphoid tissue 2001 [ 11].
Thus, relative to 3q26, these five specimens exhibited loss of 3p and 3q11, resulting in the correct classification of the specimens as ccRCC.
Despite past disagreement about the classification of these specimens, they are now usually attributed to the archaic human species H. heidelbergensis, along with other specimens such as those from Bodo Ethiopiaa), Ndutu (Tanzania), Heidelberg (Germany), and Petralona (Greece).
