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In order to perform a homogeneous and unbiased evaluation, a "clinical protocol" was developed, in which evaluation methodology, criteria for classification of alterations as severe or mild in each body area, as well as treatments were clearly specified.
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The classification of gene alterations was performed in accordance with the entries in the Breast Cancer Information Core BICC, Bethesda, MD).
First, classification analyses were conducted to explore global alteration of miRNAs by the AA treatment.
Baumbusch, L.O. et al. Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors.
Yono M, Foster HE Jr, Shin D, Mane S, Latifpour J. (2005) Molecular classification of doxazosin-induced alterations in the rat prostate using gene expression profiling.
In the present study, ARL cases were classified according to the fourth edition of the WHO classification of lymphomas, and alterations in the clinicopathological characteristics of ARL due to the introduction of ART were investigated.
These new datasets enable many applications, including clustering of cancer subtypes, prediction of survival times, and classification of cancer metastasis by analyzing DNA alterations using tools developed for RNA-level analysis.
Classification of these disorders is usually based on alterations in function or structure [ 13].
Implementing ThinPrep did not result in major alterations of the cytological classification of smears, and it did not affect CIN detection rates.
Goodness of classification was determined using the area under the receiver operating characteristic curve, with 1 indicating perfect recognition of all alterations and 0.5 indicating random classification of the variation.
Patterns of copy number alteration have proven valuable in classification of cancer subtypes and can serve as predictors of patient outcome [19].
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