On univariate analysis, RPA classification, Child-Pugh's classification, intratumoral hemorrhage, and treatment modality showed statistical significance.
Presence or absence of cirrhosis was analysed and, if cirrhosis was present, the extent was classified according to the Child Pugh classification (Child and Turcotte, 1964).
Each follow-up session includes a detailed history and physical examination, ECOG performance status classification, Child pugh score evaluation, and an abdominal enhanced CT/MRI scan.
Even widely used measures of liver function such as the C-P classification (Child and Turcotte, 1964; Pugh et al, 1973), which was developed for patients with cirrhosis rather than HCC, is remarkably subjective.
Routine liver and renal function tests (including cystatin C) were measured and the severity of the liver disease was defined according to the Child's classification (Child and Turcotte, 1964; Pugh et al, 1973) and the model for end-stage liver disease (MELD) score (Kamath and Kim, 2007).
We have taken into account the liver cirrhosis classification (Child-Pugh) as a successful model, an analogy that seems applicable in CP as well, because most recently, several authors have described common mechanisms for liver and pancreatic fibrogenesis with a resulting loss in organ function at the end stage of both diseases[ 41- 43, 59, 60].
Based on our findings, serum PBDE concentrations from a parent may be a good indicator of his/her child's levels, which could reasonably be used for a classification of children into low/medium/high categories in an epidemiology study.
Last year, I had to label my son M.D. (multiply disabled), a broad classification for children with a combination of learning problems.
To our knowledge, this is the first epidemiological study presenting the prevalence of TMD-diagnoses according to the RDC/TMD classification among children and adolescents younger than 14 years of age.
