The signed-ranks test was used to compare PhenX self-reported weight and BMI with measurements at PMRP enrollment, simple kappa statistics and 95% CL were calculated for nominal categories and Fleiss-Cohen weighted kappas and 95% CL for ordinal classifications as appropriate.
However, full clinical validation of EEC study outcomes is required for their classification as an appropriate alternative to natural allergen exposure for AIT product efficacy assessment.
The homogeneities of the dichotomized groups appeared to be satisfactory; we therefore consider the classification system as appropriate to describe the dental functional status of a population.
This may result in some misclassification with respect to unmeasured exposure to carcinogens via the mothers' work, but we expect that in the analysis of social class and brain tumour risk, fathers' OSC classification is as appropriate an exposure measure as would be one based on mothers' OSC.
It was felt amongst Obstetricians that classification as 'high-risk' is appropriate for women with raised BMI because of the increased risk of intrapartum complications.
Despite the obvious benefits of reporting "definitely pathogenic" mutations, other identified variants that currently lack sufficient evidence should also be reported, along with the appropriate classification as this will enable future reports with additional studies to confirm pathogenicity.
Despite an appearance that resembles hyaline cartilage, these tumors retain an epithelial phenotype and express specific chordoma markers, including cytokeratin and S-100, which are not found in cartilaginous tissue; this has suggested their alternative, more appropriate classification as "hyalinized chordomas" [ 22].
Both species are listed by the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) as appropriate "under certain circumstances" for evaluating the relative allergenicity of high-molecular-weight (HMW) proteins (UN, 2007b), but there has been only limited experience in their use for testing LMW sensitizers.
Therefore, the COBRA dataset will always include raw height, weight and BMI data, so that other classifications can be used flexibly and as appropriate.
To define work types, our protocol would need a type system similar to MIME to reduce "work" into fundamental units, while allowing our classification to adapt to new types of work as appropriate.
For example, the subcellular localization of BcWRKY25 and BcWRKY40 proteins was in the nucleus, which was appropriate for TFs, thus supporting their classification as functional TFs [ 35].
