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Experiments in healthy mice showed about five-fold lower plasma levels of MAG-CPT compared to the highest tolerated dose of CPT administered in classical vehicles (Caiolfa et al, 2000).
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In this paper a new visual interactive approach for the classical vehicle routing problem with backhauls (VRPB) and its extensions is presented.
Firstly, the problem is reduced to the classical vehicle routing problem within a time window.
The generalized vehicle routing problem (GVRP) is a natural extension of the classical vehicle routing problem (VRP).
The split delivery vehicle routing problem (SDVRP) is a variant of the classical vehicle routing problem in which a customer's demand can be split among several vehicles.
The HFFVRP is a variant of the classical vehicle routing problem (VRP) and has attracted much less attention in the operational research (OR) literature than the classical VRP.
A general mixed integer programming mathematic model of VRP-SDPTW is constructed, it can transform into other classical vehicle routing problems by setting different parameters.
The purpose of this study is introduction of a local search heuristic free from parameter tuning to solve classical vehicle routing problem (VRP).
In addition, this framework accommodates various restrictions that are not considered in classical vehicle routing models, but that regularly appear in practice.
This paper deals with the heterogeneous fixed fleet vehicle routing problem (HFFVRP) which is a generalization of the classical vehicle routing problem (VRP) in the sense that the fixed fleet of vehicles is assumed to be heterogeneous.
The two-dimensional loading heterogeneous fleet vehicle routing problem (2L-HFVRP) is a variant of the classical vehicle routing problem in which customers are served by a heterogeneous fleet of vehicles.
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