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Thus, they seem to have the capacity to present antigen to Th cells and receive support through the classical pathways.
Gene ontology and KEGG pathway analysis identified 18 classical pathways that were remarkably enriched, such as neurotrophin signaling pathway, VEGF signaling pathway and P53 signaling pathway.
They presumably activate these transcriptional events through classical pathways involving canonical BMP receptors.
In Ornithodoros moubata, this activity is due to protein OmCI which inhibits both the alternative and classical pathways.
In the loci conserved in other bacteria, the degradation of sucrose seems to involve more classical pathways (for review see [70]).
In experimental stroke, the complement system is also activated through non classical pathways (either the alternative or the lectin pathways) [6], [7].
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Complement activation occurs by two routes, called the classical pathway and the alternative pathway, or properdin system.
In some, the classical pathway is activated whilst in others the alternative pathway [31, 33].
The methodology can be easily scaled and adapted for classical pathway as well.
This immune inflammation involves activation of the complement cascade via the classical pathway.
C4BP has been shown to inhibit the classical pathway whilst Factor H inhibits the alternate pathway [85].
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