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On one hand, this could suggest that requirements of RBC transfusion, presumably imposed by persistent tissue dysoxia, could represent a very potent prognostic factor even when adjusted to the classical determinants of death in this setting.
We found that homocysteine was associated with classical determinants, but did not differ between individuals from long-lived families compared to their environmentally matched partners, nor did age-related increase in homocysteine concentrations.
We found a positive association between plasma homocysteine concentrations with cardiovascular disease prevalence, and with classical determinants of homocysteine such as age, sex, creatinine, vitamin B12 and folate, and MTHFR genotype.
The classical determinants, namely, age, body mass index and sex traits, were constantly used in all models to further identify RA-related and non-RA-related parameters which were associated with the dependent variables.
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A generalization of classical determinant inequalities like Hadamard's inequality and Fischer's inequality is studied.
However, unlike many bacterial pathogens, M. pneumoniae lacks numerous classical virulence determinants, such as specialized virulence-associated secretion systems (type three/four) and their associated secreted virulence products.
The classical Lewis determinants (Lea and Leb) are composed of type 1 chains [ 1].
Overall there was a lack of what might be considered classical virulence determinants when compared with S. pyogenes.
The IBD isolates did not carry any of the classical virulence determinants characteristic of intestinal pathogenic E. coli (Table 4).
There are two classical virulence determinants expressed by H. pylori, the CagA protein encoded by the cytotoxin-associated genes pathogenicity island (cagPAI) and the vacuolating cytotoxin (VacA).
The amalgamation of this new prognostic score into the set of classical prognostic determinants might be useful when prognostic studies are evaluated.
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