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The class I gene family is divided into the classical class Ia genes and the non-classical class Ib genes.
We called this group of genes classical Class A cancer hypermethylated genes (Tables 1 and S1).
Ligands of inhibitory NK receptors are classical class I molecules, such as H2K and H2D.
In this study, only the classical class II region containing alpha and beta genes was sequenced.
Larval Xenopus reportedly lack MHC classical class I expression [33] suggesting the antiviral response in larvae may be compromised.
HLA-F and HLA-G belong to the non classical class I type genes and their function is under study.
Similar(16)
Previous studies have focused on classical class-I and -II regions and showed that polymorphisms in these regions were associated with chronic hepatitis C [ 6– 8].
KIR2DL4 binds the "non-classical" class I molecule HLA-G.
We found only non-classical class I genes in close proximity to antigen processing genes.
Clear orthologs of non-classical class I are conserved in distant marsupial lineages.
This sequence may represent an ancient lineage of non-classical class II genes in reptiles.
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