Exact(29)
Antimicrobial peptides (AMPs) have significant potential as alternatives to classical antibiotics.
As an alternative to classical antibiotics, nanoparticles with antibacterial properties are on the top of the scientific research current topics.
In contrast to classical antibiotics, these peptides act by direct physical destabilization of the target cell membrane.
In addition, AMPs also showed synergy with classical antibiotics, neutralize toxins and are active in animal models.
Extensive use of classical antibiotics has led to the growing emergence of many resistant strains of pathogenic bacteria.
In recent years, antimicrobial peptides (AMPs) has received significant attention as an ideal alternative to classical antibiotics because of their unique antimicrobial properties (Fox 2013).
Similar(31)
By targeting drug delivery (e.g. ligand grafted surface), these nanogels can be used to prevent biofilm formation and control infection without the complications (i.e. overexposure) associated with classical antibiotic delivery platforms.
Nevertheless, we must remember that after HGT, classical antibiotic resistance genes are displaced from the genetic background in which they evolved and their function in the original organism is not necessarily antibiotic resistance.
Eventually, this dissemination will jeopardize classical antibiotic treatments in patients at risk.
In consideration of the increasing number of multiresistant strains, RiPPs are a promising alternative to classical antibiotic treatment.
The presence and the transmission of such a multidrug-resistant Salmonella infection constitute a major concern, since such strains could jeopardize classical antibiotic therapy in patients at risk.
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