Sentence examples for classic regulators from inspiring English sources
In addition to classic regulators of neurogenesis, cis-Decoder reveals additional conserved novel elements that are widely distributed or only detected in pairs of enhancers.
One of the principal classic regulators of autophagy is MTOR (mechanistic target of rapamycin [serine/threonine kinase]), named because the pharmacological agent rapamycin induces autophagy by blocking MTOR signaling.
Vertebrate c-Myc is a classic regulator of genes involved in cell cycle progression.
TNF-α is a multifunctional pro-inflammatory cytokine that is viewed as a classic regulator of cell death and is also activated by ER stress [ 36].
A number of classic cytoskeletal regulators are autonomously required within hemocytes for dispersal or normal motility, including the GTPases Rho, Rac and Cdc42 [ 14,15], and actin regulators Ena [ 6] and fascin [ 16,17 ]; all these play related roles in vertebrate cells.
Furthermore, although classic feedback regulators of mitogen-activated protein kinase (MAPK) pathways have been described, such as dual-specificity phosphatases (DUSPs) for ERK and c-Jun N-terminal kinase (JNK) (Li et al., 2007; Owens and Keyse, 2007), the extent of effector-dependent transcription genome-wide is not well characterized.
Whether or not Che3 signaling ultimately regulates timing of encystment directly, through the phosphorylation of a classic response regulator, or does so by means of a more indirect mechanism remains to be elucidated.
It is a classic captured regulator.
To Mr. Kalanick, the rules being proposed by Mr. Daus's committee are a classic example of regulators trying to stifle innovation.
pRb is known as a classic cell cycle regulator whose inactivation is an important initiator of tumorigenesis.
