Sentence examples for classes of variation from inspiring English sources

These two classes of variation represent two general mechanisms of modifier action.

A map of these two classes of variation has yet to be constructed.

It is likely that additional rare inherited variant types will be associated with ASDs as sequencing studies increase in sample size and new techniques are developed to filter and highlight classes of variation most likely to be deleterious.

In addition, other classes of variation, such as short insertion deletion variants (indels), as well as copy number variants (CNVs) and structural variants (SVs), are even more difficult to detect using high-throughput sequencing.

Nevertheless, this class of variation harbours multiple penetrant disease mutations conferring medium to high risk.

The increased incidence of CNV14q12 in tumor samples suggests that either acquired or inherited genomic variation of this new class of variation may be associated with onset or progression of neoplasia.

Although GWAS have proven extremely effective at identifying common variants with relatively large effects, the first wave of data suggests that for many diseases, this class of variation accounts for only a small fraction of the genetic risk.

We find similar results when TEs are considered as a class of variation as has been done previously on smaller scales (Mackay and Langley 1990; Long et al. 2000; Macdonald et al. 2005; Gruber et al. 2007).

Furthermore, while individual insertions are private to a single DGRP line, as a class of variation these insertions are common and frequently insert into regions that may produce changes in expression.

Several previous studies that found associations between TEs and variation have done so by examining TEs as a class of variation, where all TEs are expected to contribute to phenotypic variation in the same way (Mackay and Langley 1990; Long et al. 2000; Macdonald et al. 2005; Gruber et al. 2007).

We developed single color ddPCR assays to measure two classes of genetic variation: (1) copy number variations and (2) SNVs.