Sentence examples for classes of splice from inspiring English sources

We present genome-scale software to quantify the effect of mutations in the common classes of splice donor (U1) or acceptor (U2 -type sites in a high-throU2 -typeanner.

EMT-associated splicing events are regulated by a variety of classes of splicing factors, and deregulation of these factors may lead to EMT transition and tumor metastasis (Shapiro et al. 2011).

Results: In this short report, we present a framework that generalizes the metric to arbitrary classes of splicing events.

We next extended this analysis to all classes of splicing events, including mis-splicing and intron retention of constitutive splice junctions.

Among the RBPs, the major classes of splicing factors that control splice site recognition are the families of Serine/Arginine-rich (SR) proteins and heterogeneous nuclear ribonucleoproteins (hnRNPs).

DUX4 expression caused increased levels of predicted NMD substrates for all classes of splicing events in both 54-1 and MB135 cells.

We have evaluated the nine classes of splicing events in clusters in which at least one alignment assembly incorporates a FL-cDNA.

Results have pointed to several classes of splicing kinetics for coding and non-coding RNAs, including remarkably inefficient processing of small nucleolar RNAs.

Along with unspliced genomic RNA, the pool encompasses two major classes of spliced transcripts, a 1.8 kb class and a 4 kb class, which derive from the combinatorial usage of five 5′ donor and eight 3′ acceptor sites.

Prior research has shown that the classes of splicing variations observed through comprehensive analyses in Arabidopsis are similar to that observed in mammalian systems [ 5, 12, 15, 16, 31].

Among the classes of splicing regulatory regions analysed, SNPs that occurred in donor sites were slightly more likely to be confirmed by EST and/or exon array data (Table 1).