Sentence examples for classes of pathways from inspiring English sources

Pathways and classes of pathways.

As a result, a clear separation between unfavourable/favourable miRNAs was obtained (bootstrapping p-value < 10-4), indicathat theirtheir opposite prognostic values are reflected in the association with different classes of pathways.

40 Our data suggest that MLL fusions induce the upregulation of the receptor tyrosine kinase Csf-1r and Hox genes, thereby inducing the rapid onset of AML by activating two classes of pathways (Fig. 7).

A group of metabolites, such as those from a metabolomics experiment, can be subjected to enrichment analysis with respect to the set of pathways and classes of pathways that include those metabolites as substrates.

We initially defined two main classes of pathway activation metrics on a given gene module.

One such class of pathways is involved in the biogenesis of Iron-Sulfur Clusters (ISC).

The remaining class of pathways is "perturbation-specific" responses: they are significant for only one perturbation in a cell type, which may or may not drive overall significance for all conditions.

The second class of pathways (along the path λ and ν in Figure 3) exhibits two steps and represents the degradation processes (independent of miRNAs) passing through a control step of a more complex degradation pathway (e.g. the preliminary binding of specific proteins to the target mRNA).

The first class of pathways (governed by the rate µ in Figure 3) is characterized by a single step and it can be representative of the set of "constitutive" reactions which target mRNAs non-specifically and are catalyzed by enzyme complexes such as the exosome [ 9].

With this DoD grant, Singh aims to develop a lymphoma subtype-specific organoid that can be used to understand the role of the tumor microenvironment in ABC-DLBCLs, to better evaluate the pre-clinical and clinical outcomes of a new class of pathway targeting, anti-tumor therapeutics that the team has developed.

Peptides are the backbone of most pathway processes and by far the most abundant class of pathway object in Reactome.