Sentence examples for classes of modifications from inspiring English sources

By using explicit chemistry to represent modified regions we can search across classes of modifications for common features.

We chose antibodies that represent the different classes of modifications present on the array (lysine and arginine methylation, phosphorylation, and acetylation).

In this context, the proteins and domains that recognize histone modifications, named "effectors" or "readers", are thought to define the functional consequences of many classes of modifications by transducing molecular events at chromatin into biological outcomes.

No significant difference was apparent between these three classes of modification with regard to cloning efficiency, pregnancy and delivery rate.

Of the three classes of epigenetic modifications, posttranslational modification of histone proteins undoubtedly is the most complex.

At present, several classes of histone modifications and their respective enzymatic modification systems have been identified (Table 1) [ 26].

At present several classes of histone modifications and their respective enzymatic modification systems have been identified [ 72, 75] and amongst their epigenetic substrate marks, lysine and arginine modifications are probably the best studied: acetylation and methylation of lysine residues, as well as methylation of arginine [ 72, 75, 76].

As lysine methylation does not change the side-chain charge, this class of modification exerts its biochemical effects predominantly by serving as a docking platform for protein protein interactions.

This finding suggests a mix-and-match evolutionary pattern for post-translationally modified peptide biosynthesis and export systems, in which similarity in the leader peptide region provides only indirect evidence of which class of modification (thiazole/oxazole versus lanthionine) will occur.

The molecular turnover rates for two classes of chromatin modifications believed to record and store durable memories were approximated from experiments using diverse approaches and were found to be remarkably short.

With the advent of genome-wide profiles of DNA methylation (Bonasio et al. 2012) and hPTMs (Simola et al. 2013) for distinct castes of the Florida carpenter ant Camponotus floridanus, it is now possible to investigate how these two important classes of epigenetic modifications relate to one another at a fine spatial scale.