Sentence examples for classes of insertion from inspiring English sources

To better understand specificity, we compared different size classes of insertion and deletion to the Database of Genomic Variants (DGV, http://projects.tcag.ca/variation/, [ 25]) as in [ 24].

For example, most bacteria harbor multiple classes of insertion sequence (IS) elements, which average about a kilobase in length and whose copy numbers are highly variable, sometimes reaching hundreds of copies per genome [ 7, 8].

More importantly, analysis of the RelocaTE output by CharacTErizer permitted the accurate identification of many more classes of insertions from old (homozygous) to newer (heterozygous) to the newest events including somatic insertion and excision events.

We identified approximately 20 loci that correspond to a single class of insertion sequences of the IS605 family [ 12].

This observation largely accounts for the fact that the annotated set is also enriched in long TEs, since LTR insertions tend to be longer than other classes of TE insertion in the genome [ 14].

Germline and somatically derived inversions and transpositions were present in approximately equal frequencies while somatically derived SVs were more frequent than germline derived variants for all other classes of SVs (insertions, inverted-duplications, tandem duplications and translocations).

The annotation of ME-Scan loci with RepeatMasker information reveals three classes of loci: AluYb8/9 insertions present in the reference genome; other (mostly older) Alu elements also present in reference that amplified sporadically in ME-Scan, despite lacking perfect primer binding sites; and those that could not be annotated and presumably represent new AluYb8/9 insertions.

The other common class of mutations, insertions and deletions (indels), are also affected by selection.

In two of the aforementioned studies of T-cell lymphomas, a second class of retroviral insertions within the Notch1 gene has been described [ 38, 39].

In addition, this method is capable of eliminating, without a defined age threshold, the older class of TE insertions as being candidates for recent adaptation.

Our PCR data are consistent with this observation and our model also performs well in predicting the fixation of the older class of TE insertions largely residing in regions of low recombination.