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There are five classes of histone.
Two classes of histone lysine demethylases remove histone methylation.
To date, two distinct classes of histone demethylases have been characterized.
Rice genome possesses multiple genes encoding different classes of histone modification enzymes.
In metazoans, there are two classes of histone proteins.
The replication-dependent histone genes whose activity is shown in Figure 2 represent all the classes of histone proteins present in the nucleosome core complex.
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The internal structure and boundaries of functional centromeres are strongly associated with histone modifications and with centromere-specific classes of histones [16], [17].
There are five major classes of histones: the core histones H2A, H2B, H3, and H4 and the linker histone usually referred to as H1.
This includes loci of certain classes of histones, transcribed coding genes, CpG islands, transcription factors and miRNA target sites (21, 51, 52).
Importantly, among the five classes of histones, the H1 linker histone exhibits the greatest mobility, shuttling between the chromatin and the nucleoplasm with a residence time in chromatin of approximately 3 min [ 6, 7].
We propose here a unified nomenclature for variants of all five classes of histones that uses consistent but flexible naming conventions to produce names that are informative and readily searchable.
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