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We hypothesized that the alterations in the predicted active sites of the two classes of divergent FENs would lead to pronouncedly different catalytic activity.
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We conclude that DNA specificity and functional surface specialization has independently driven nuclear receptor evolution, and suggest possible binding modes for the class of divergent nuclear receptors in nematodes.
WD-repeat proteins are a class of functionally divergent molecules that cooperate with other proteins to regulate cellular processes.
ORs appear to have evolved exclusively within insects and form heteromeric ion channel complexes consisting of at least two subunits: One a highly conserved coreceptor (Orco) whereas the other (ORx) belongs to a class of highly divergent ligand-specifying partners (Clyne et al. 1999; Vosshall et al. 1999; Larsson et al. 2004; Sato et al. 2008; Missbach et al. 2014).
Identifying the classes of genes under divergent selection provides insight into the factors most strongly involved in divergence among these hybridizing taxa, but warrants future direct investigation of the role of ecological factors in speciation and maintenance of species boundaries.
For the mouse, macaque, and dog genomes, three classes of CTCF sites (conserved, divergent present, divergent absent) and TSS sites were defined.
The optimal result was later obtained by Sathaye (see [16]) who showed that the class of convergence sets of divergent power series (f(x_{1},x_{2})) is precisely the class of (F_{sigma }) polar sets in (mathbb {P}^{1}).
Because the ample gene flow between the wealth-classes likely decreased the rate of divergent evolution between the wealth classes, it is also plausible that the phenotypic trait means between the wealth classes differed due to phenotypic plasticity.
Each was excellent, but being of divergent weight classes, they did not belong together in the ring.
Here, we explore the architecture of four members of the IGR IRESes, representative of the two divergent classes of these IRES RNAs.
Initial comparisons of the human and mouse genome sequences revealed three classes of genes associated with divergent coding regions, those encoding extracellular, immune system, and reproductive proteins [ 20].
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