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To identify transcripts that were specifically enriched by association with PUM1 and PUM2, we performed two class Significance Analysis of Microarrays (SAM) on median centered arrays [45].
They were also shorter in response to proper (717 ms) than common (752 ms) nouns, as shown by lexical class significance (F 1,13) = 47.19, p<0.01).
To perform microarray analysis a two unpaired class Significance Analysis of Microarray (SAM) test was carried out on normalized data.
A two-unpaired class Significance Analysis of Microarray (SAM) test was carried out on normalized data, enforcing a False Discovery Rate (FDR) of 3%.
We performed an unpaired two class Significance Analysis of Microarrays (SAM; Tusher et al, 2001) with class no. 1 including immune system-related tissues and white blood cells and class no. 2 including all other tissues.
A two-unpaired class Significance Analysis of Microarray (SAM) test was conducted on normalized data between individuals from the Tiber (N = 8 males) and Bolsena (N = 7 males) sites.
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The interacting drug classes, significance, reliability, and clinical management of the interactions were recorded in a database.
Differentially expressed genes were then identified using one-class Significance Analysis of Microarray (SAM) at a 5% false discovery rate (FDR) using TIGR MeV [47], [48].
In a two-class Significance Analysis of Microarrays (SAM) analysis [22], 2,088 significantly differentially expressed genes were identified using a false discovery rate (FDR) of less than 1%, hereafter termed the "c-Myb gene signature" (Table S2).
Two-class Significance Analysis of Microarrays (SAM) [49] was used to identify genes that were differentially expressed in CLM compared to primary CRC and normal liver (a potential contaminant of CLM), with statistical significance assessed by a false discovery rate (FDR).
These filtered genes were analyzed by the multi-class Significance Analysis of Microarrays (SAM) algorithm [23] to select a set of ∼4000 genes that were consistently differently expressed between skin from AE patients and control individuals, with a false discovery rate less than 0.26% (Supplementary Table S1).
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