Fluoroquinolones and cephalosporins are two classes of veterinary antibiotics arising as pollutants of emerging concern.
In this paper, we examine different analytical approaches in assessing Kd of two major classes of veterinary antibiotics (sulfonamides and macrolides) and compare the existing literature data with experimental data obtained in our laboratory.
Many papers have tackled the analysis of different classes of veterinary antibiotics in milk using LC-MS/MS (Bogialli et al. 2008; Hermo et al. 2008; Han et al. 2015, and Meng et al. 2015).
A multiclass method was proposed for the simultaneous determination of various classes of veterinary drugs (n = 65), mycotoxins and metabolites (n = 39) in egg and milk by ultra-high performance liquid chromatography-tandem mass spectrometry.
However, not all classes of veterinary drugs were tested on the described studies.
There is an increasing interest in screening methods for quick and sensitive analysis of various classes of veterinary drugs with limited sample pre-treatment.
Milk was selected as the test matrix because it is an important matrix for residue control which can contain residues from different classes of veterinary drugs.
Turnipseed et al. [ 4] described a method for the analysis of different classes of veterinary drugs in milk using LLE followed by SPE and LC-MS/MS.
