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Here, we report a new class of reagents based on transcription activator-like effector nucleases (TALENs) to disrupt myostatin expression at the genome level.
Engineered binding proteins derived from non-antibody scaffolds constitute an increasingly prominent class of reagents in both research and therapeutic applications.
These results suggest that thiacycloheptynes constitute a promising class of reagents for Cu-free click chemistry.
In conclusion, thiacycloheptynes are a promising new class of reagents for bioorthogonal Cu-free click chemistry.
Among this class of reagents are several monoclonal antibody-anti CD3 scFv fusion reagents, some of which have undergone clinical evaluation with strong evidence of efficacy [ 14– 17].
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A third class of reagent designed to covalently attach to peptides utilizing carbene insertion chemistry is also presented.
In order to directly compare substrate and ABP imaging agents, we evaluated both classes of reagents in a simple xenograft mouse model of cancer.
We have three classes of reagent: primary RTK inhibitors, growth factor ligands, and secondary RTK inhibitors.
Application of tyrosinase, which is sensitive to some classes of reagent only, can also reduce the problem of many interfering compounds in biological systems, for example ascorbic acid (AA), uric acid (UA), and other neurotransmitters.
Our solution to the affinity reagent problem is to develop a new class of affinity reagents that can be developed in a high-throughput manner using minimal amounts of protein.
Recombinant immunoconjugates constitute a novel class of immunoassay reagents produced by genetic fusion between an antigen recognizing moiety and a reporter enzyme or fluorescent protein, obviating the need for chemical coupling.
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CEO of Professional Science Editing for Scientists @ prosciediting.com